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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404749Generated: October 29, 2026

Hydrochloric Acid → HCID 68593072, compound

https://huagongshe.com/reaction/404749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant6-Bromo-7-chloroisoquinolineHCID 53418615—
ReactantHCID 68593104HCID 68593104—
ProductHCID 68593072HCID 68593072—

Reaction Steps

Starting from 6-Chloro-7-chloroisoquinoline (263) and 2-Bromomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 7-Chloro-6-(pyrrolidin-2-ylmethylsulfanyl)-isoquinoline could be obtained according to the procedures described for 272, 267, 268 as the hydrochloride. Rt=0.85 min (Method B). Detected mass: 279.1/281.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748614B2
Source datasetuspto-grants-2014_06
ORD IDord-c54819c117db4a4c998b2fdc9bd4ff7e
Source noteuspto-grants-2014_06