Water → 4,8-Bis(10-phenyldecyl)-2,6-bis-trimethylstannylbenzo[1,2-b:4,5-b']dithiophene

HRID 405047Notes

Reaction equation

HRID 405047 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]2[C:25]3[S:26][CH:27]=[CH:28][C:24]=3[C:23]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)=[C:19]3[S:20][CH:21]=[CH:22][C:18]=23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([Li])CCC.[CH3:50][Sn:51](Cl)([CH3:53])[CH3:52].O>O1CCCC1>[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]2[C:25]3[S:26][C:27]([Sn:51]([CH3:53])([CH3:52])[CH3:50])=[CH:28][C:24]=3[C:23]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][C:39]3[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=3)=[C:19]3[S:20][C:21]([Sn:51]([CH3:53])([CH3:52])[CH3:50])=[CH:22][C:18]=23)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

6

Reactant 4

HCID 962WaterHCID 14016Trimethyltin chlorideHCID 668211144,8-Bis(10-phenyldecyl)benzo[1,2-b:4,5-b']dithiopheneHCID 178418339Butyllithium

Product 1

HCID 866482724,8-Bis(10-phenyldecyl)-2,6-bis-trimethylstannylbenzo[1,2-b:4,5-b']dithiopheneYield 70%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a solution of 4,8-bis(10-phenyldecyl)benzo[1,2-b:4,5-b′]dithiophene (466 mg, 0.75 mmol) in dry tetrahydrofuran (15 mL) was added n-butyllithium (2.5 M in hexane, 0.66 mL, 1.65 mmol) at −78° C. After 1 hour, trimethyltin chloride (349 mg, 1.75 mmol) was added in one portion. The mixture was stirred at room temperature overnight, poured into water (25 mL) and extracted with ether three times. The organic layer was washed with brine and dried over anhydrous MgSO4. Upon evaporating the solvent, a pale yellow oil was obtained (500 mg, yield 70%). 1H NMR (CDCl3, 500 MHz) δ=7.49 (s, 2H), 7.27-7.32 (m, 4H), 7.17 (d, J=7.5 Hz, 6H), 3.19 (t, J=7.5 Hz, 4H), 2.59 (t, J=8.0 Hz, 4H), 1.75-1.84 (m, 4H), 1.56-1.66 (m, 4H), 1.42-1.50 (m, 4H), 1.17-1.41 (m, 20H), 0.45 (s, 18H).

Workup

  1. extractionextracted with ether three times
  2. washThe organic layer was washed with brine
  3. dry with materialdried over anhydrous MgSO4
  4. customUpon evaporating the solvent
  5. customa pale yellow oil was obtained (500 mg, yield 70%)

Sources & evidence

ORD record
ord-129d252e5cb5448991f4756f7643dc9e
Source dataset
uspto-grants-2014_06
Patent number
US08748739B2

Reaction notes

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