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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 405248Generated: October 29, 2026

4-Chlorophenylboronic acid → 2,4',6-Trichloro-[1,1'-biphenyl]-4-amine

https://huagongshe.com/reaction/405248

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant4-Bromo-3-chloroanilineHCID 88888—
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Reactant4-Bromo-3,5-dichloroanilineHCID 13749710—
Product2,4',6-Trichloro-[1,1'-biphenyl]-4-amineHCID 68131025—

Reaction Steps

The title compound was prepared as described in Example 159 substituting 4-bromo-3,5-dichloroaniline and (4-chlorophenyl)boronic acid for 4-bromo-3-chloroaniline and (4-(trifluoromethyl)phenyl)boronic acid, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748624B2
Source datasetuspto-grants-2014_06
ORD IDord-be48c29f54e94c7996f52d7909cc6a32
Source noteuspto-grants-2014_06