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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 405916Generated: October 30, 2026

HCID 66863463, compound → HCID 86650195, compound

https://huagongshe.com/reaction/405916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66863463HCID 66863463—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 86650195HCID 86650195—

Reaction Steps

5 g ethyl 3-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole-6-carboxylate and 2.3 g palladium hydroxide are suspended in 180 ml of methanol and hydrogenated at 50 psi for 2 hours at ambient temperature. The catalyst is suction filtered and the mother liquor is evaporated to dryness. 3.6 g (V-2) are obtained as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754073B2
Source datasetuspto-grants-2014_06
ORD IDord-14b3e489cc1a402db96dbd3af0150787
Source noteuspto-grants-2014_06