HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58117567, compound → (S)-5-amino-1-propylpiperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58117567 | HCID 58117567 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (S)-5-amino-1-propylpiperidin-2-one | HCID 58117851 | 82.1% |
Reaction Steps
0.569 g (S)-5-dibenzylamino-1-propylpiperidin-2-one are placed in 25 ml of methanol and hydrogenated with 0.150 g Pd/C 10% at a pressure of 3 bar and a temperature of 60° C. After 19 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 0.217 g of the product are obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754073B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-e8b0e500918d4f5398e2f5c1f4dd1bf2 |
| Source note | uspto-grants-2014_06 |