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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406043Generated: October 25, 2026

2,4-Difluoronitrobenzene → 4-Fluoro-2-((1S,2S)-2-methoxy-cyclohexyloxy)-1-nitro-benzene

https://huagongshe.com/reaction/406043

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluoronitrobenzeneHCID 67967—
Reactant(1S,2S)-2-MethoxycyclohexanolHCID 10197706—
Product4-Fluoro-2-((1S,2S)-2-methoxy-cyclohexyloxy)-1-nitro-benzeneHCID 58421538—

Reaction Steps

Prepared analogously to III.1 from 926 μl 2,4-difluor-nitrobenzene and 1 g (1S,2S)-2-methoxycyclohexanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754079B2
Source datasetuspto-grants-2014_06
ORD IDord-18e7107c71734a4ebc8cb6a18c00d973
Source noteuspto-grants-2014_06