Hydrochloric Acid → HCID 178475043, compound

Participants

Reaction Steps

A mixture of 0.15 g [2-({4-[2-(trans-3-acetylamino-cyclobutoxy)-4-fluoro-phenylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carbonyl}amino)-cyclopropyl]-carbamic acid tert-butyl ester in 5 ml dioxane was added 1 M hydrochloric acid solution in Dioxan and was stirred at rt overnight. The reaction mixture was concentrated and the residue was purified by chromatography.

Provenance & Evidence