HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Bis(4-methylphenyl)-1,2-ethanedione → 7-Chloro-2,3-dip-tolylpyrido[2,3-b]pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Bis(4-methylphenyl)-1,2-ethanedione | HCID 76996 | — |
| Reactant | 5-Chloropyridine-2,3-diamine | HCID 1268254 | — |
| Reactant | (E)-7-(2,3-Diphenyl-7,8-dihydropyrido[3,2-b]pyrazin-5(6H)-yl)hept-3-enoic acid | HCID 66665765 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 7-Chloro-2,3-dip-tolylpyrido[2,3-b]pyrazine | HCID 66666349 | — |
Reaction Steps
The title compound was prepared from 1,2-dip-tolylethane-1,2-dione and 5-chloro-pyridine-2,3-diamine analogously to 2,3-dip-tolylpyrido[2,3-b]pyrazine (Intermediate E step 1). Acetic acid is not used in this reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754085B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-4f258bbbcb2b41c89c6374e8bbe07a28 |
| Source note | uspto-grants-2014_06 |