反应详情

Methyl 3-oxiranyl-2-(2-trifluoromethylphenyl)propionate (2.61 g) was dissolved in ethanol (20 mL). Hydrazine monohydrate (2.3 mL) was added at room temperature, and the mixture was reacted for 24 hours. Concentration under reduced pressure gave an oil which was partitioned with methylene chloride and water. The aqueous layer was extracted with methylene chloride four times. After drying over magnesium sulfate, concentration under reduced pressure gave the title compound (1.8 g) as a pale yellow solid.

1. customthe mixture was reacted for 24 hours
2. concentrationConcentration under reduced pressure
3. customgave an oil which
4. customwas partitioned with methylene chloride and water
5. extractionThe aqueous layer was extracted with methylene chloride four times
6. dry with materialAfter drying over magnesium sulfate, concentration under reduced pressure