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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 406413Generated: October 27, 2026

Benzamide → HCID 178487740, compound

https://huagongshe.com/reaction/406413

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamideHCID 2331—
Reactant3,5-Difluorobenzoyl chlorideHCID 145600—
Reactant2-Amino-4-methoxy-3-methylbenzamideHCID 59165435—
ProductHCID 178487740HCID 17848774085%

Reaction Steps

The general procedure described in Example 10 was followed using 2-amino-4-methoxy-3-methyl benzamide as benzamide derivative [A] and 3,5-difluoro-benzoyl chloride as acid chloride [B], which gave the title compound (2.1 g, 85%), [M+H]=303.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754105B2
Source datasetuspto-grants-2014_06
ORD IDord-acadc822c3a04807bba75b0511f2452d
Source noteuspto-grants-2014_06