N-(tert-butoxycarbonyl)glycine → HCID 69227387, compound
Reaction equation
[CH3:1][C:2]1([N:7]2[CH2:12][CH2:11][CH:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH2:9][CH2:8]2)[CH2:6][CH2:5][NH:4][CH2:3]1.C(OC([NH:26][CH2:27][C:28](O)=[O:29])=O)(C)(C)C>>[NH2:26][CH2:27][C:28]([N:4]1[CH2:5][CH2:6][C:2]([CH3:1])([N:7]2[CH2:12][CH2:11][CH:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH2:9][CH2:8]2)[CH2:3]1)=[O:29]Participants
3
Procedure
The title compound was prepared from 1-(3-methylpyrrolidin-3-yl)-4-phenylpiperidine and 2-(tert-butoxycarbonylamino)acetic acid using general procedures G, F.
Sources & evidence
- ORD record
- ord-530a8bb05bdf4199a6612378406eaf5f
- Source dataset
- uspto-grants-2014_06
- Patent number
- US08754107B2
Reaction notes
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