Iodoethane → 5-bromo-1-ethyl-3-methylpyridin-2(1H)-one

HRID 406725Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([CH3:9])[C:5](=[O:8])[NH:6][CH:7]=1.[CH2:10](I)[CH3:11]>>[Br:1][C:2]1[CH:3]=[C:4]([CH3:9])[C:5](=[O:8])[N:6]([CH2:10][CH3:11])[CH:7]=1

Participants

Reactant 2

HCID 6340Iodoethane

HCID 2854365-Bromo-2-hydroxy-3-methylpyridine

Product 1

HCID 667358175-bromo-1-ethyl-3-methylpyridin-2(1H)-one

Procedure

5-Bromo-1-ethyl-3-methylpyridin-2(1H)-one was prepared by alkylation of 5-bromo-3-methylpyridin-2(1H)-one with ethyl iodide following a procedure analogous to that described in Example 59 Step 1.

Sources & evidence

ORD record: ord-870fbc5ebd764467a0008d3a5889d3bf
Source dataset: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08754076B2

Reaction notes

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