HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanamine → US10213427, Example 16
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | 2-(4-{1-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl]amino)phenyl]-1H-benzimidazol-5-yl}phenyl)propanoic acid | HCID 67980254 | — |
| Product | US10213427, Example 16 | HCID 57386675 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 14 starting from 2-(4-{1-[3-({[(2,2,2-trifluoro ethyl)amino]carbonyl}amino)phenyl]-1H-benzimidazol-5-yl}phenyl)propanoic acid (prepared by the procedure for Example 14, step 3) and cyclopropylmethylamine (Aldrich, Cat. No. 359521), LCMS (M+H)+: m/z=536.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08754114B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-5d45cf382ae84178b140a0c384e34879 |
| Source note | uspto-grants-2014_06 |