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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407021Generated: October 29, 2026

3,3,3-Trifluoro-2-hydroxypropanoic acid → HCID 57384357, compound

https://huagongshe.com/reaction/407021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3,3-Trifluoro-2-hydroxypropanoic acidHCID 244896—
ReactantN-{3-[7-(1-piperidin-4-yl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]phenyl}-N'-(2,2,2-trifluoroethyl)ureaHCID 67980436—
ProductHCID 57384357HCID 57384357—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 41 starting from N-{3-[7-(1-piperidin-4-yl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]phenyl}-N′-(2,2,2-trifluoroethyl)urea and 3,3,3-trifluoro-2-hydroxypropanoic acid (Lancaster, Cat. No. L07742). LCMS (M+H)+: m/z=611.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-0fba7f03866a45fba78bd5e4c34bef6a
Source noteuspto-grants-2014_06