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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 407083Generated: October 30, 2026

(1R)-1-(2-Fluorophenyl)ethylamine → N-[1-(2-Fluorophenyl)ethyl]-3-[3-(3-{[(methylamino)carbonyl]amino}phenyl)imidazo[1,2-b]pyridazin-7-yl]benzamide

https://huagongshe.com/reaction/407083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R)-1-(2-Fluorophenyl)ethylamineHCID 2782361—
Reactant3-[3-(3-{[(Methylamino)carbonyl]amino]phenyl)imidazo[1,2-b]pyridazin-7-yl]benzoic acidHCID 67980067—
ProductN-[1-(2-Fluorophenyl)ethyl]-3-[3-(3-{[(methylamino)carbonyl]amino}phenyl)imidazo[1,2-b]pyridazin-7-yl]benzamideHCID 57386927—

Reaction Steps

This compound was prepared by using procedure analogous to those described for the synthesis of Example 96, Step 4 starting from 3-[3-(3-{[(methylamino)carbonyl]amino}phenyl)imidazo[1,2-b]pyridazin-7-yl]benzoic acid and 1-(2-fluorophenyl)ethanamine. LCMS (M+H)+: m/z=509.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08754114B2
Source datasetuspto-grants-2014_06
ORD IDord-e99d17e330a84c0ab2298a026485303a
Source noteuspto-grants-2014_06