Methylamine → HCID 178482611, compound

HRID 407358Notes

Reaction equation

HRID 407358 reaction equation
Br[CH2:2][C:3]1[CH:18]=[CH:17][C:6]2[N:7]=[C:8]([C:10]3[C:14]([CH3:15])=[N:13][NH:12][C:11]=3[NH2:16])[S:9][C:5]=2[CH:4]=1.[CH3:19][NH2:20]>>[CH3:15][C:14]1[C:10]([C:8]2[S:9][C:5]3[CH:4]=[C:3]([CH2:2][NH:20][CH3:19])[CH:18]=[CH:17][C:6]=3[N:7]=2)=[C:11]([NH2:16])[NH:12][N:13]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 178434639HCID 178434639, compound

Product 1

HCID 178482611HCID 178482611, compound

Procedure

The title compound (1.6 mg) was prepared starting from 18 mg of 4-(6-bromomethylbenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine and excess methylamine. MS (m/z, ES+): 274.1 (M+1, 100%), 243.1 (M-CH3NH, 60%).

Sources & evidence

ORD record
ord-41172c61a8864761918c59075c07f2b5
Source dataset
uspto-grants-2014_06
Patent number
US08754233B2

Reaction notes

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