HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → 5-(Trifluoromethyl)quinazoline-2,4(1H,3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | 2-Amino-6-(trifluoromethyl)benzoic acid | HCID 2778508 | — |
| Product | 5-(Trifluoromethyl)quinazoline-2,4(1H,3H)-dione | HCID 34176126 | — |
Reaction Steps
Prepared according to general method C from 2-amino-6-trifluoromethylbenzoic acid (1.0 g) and urea (2.92 g). Yield: 948 mg (85%) of a solid. 1H-NMR (DMSO-δ6) δ (ppm) 11.43 (br s, 2H), 7.78 (t, J=7.9 Hz, 1H), 7.58 (d, J=7.4 Hz, 1H), 7.48 (d, J=8.2 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08530486B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-85c7ce1600c24c7a972f69a53beef6cc |
| Source note | uspto-grants-2013_09 |