HRID40768

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1176

Urea

CH4N2O

HCID2778508

2-Amino-6-(trifluoromethyl)benzoic acid

C8H6F3NO2

PRODUCTS

生成物

HCID34176126

5-(Trifluoromethyl)quinazoline-2,4(1H,3H)-dione

C9H5F3N2O2

PROCEDURE

实验过程

Prepared according to general method C from 2-amino-6-trifluoromethylbenzoic acid (1.0 g) and urea (2.92 g). Yield: 948 mg (85%) of a solid. 1H-NMR (DMSO-δ6) δ (ppm) 11.43 (br s, 2H), 7.78 (t, J=7.9 Hz, 1H), 7.58 (d, J=7.4 Hz, 1H), 7.48 (d, J=8.2 Hz, 1H).

WORKUP

后处理

customPrepared