反应详情

温度

40 °C

Dry chloroform (30 ml) is added to a mixture of lead tetraacetate (8.52 g, 19.3 mmol) and mercuric diacetate (0.28 g, 0.875 mmol) under an atmosphere of nitrogen, and the reaction mixture is stirred and heated to 40° C. 4-Bromo-2-ethylphenylboronic acid (4.0 g, 17.5 mmol) is added in one portion and the mixture is stirred at 40° C. for 4 hours. The reaction mixture is cooled to 0° C., and potassium carbonate (2.66 g, 19.3 mmol) is added portionwise. The mixture is stirred for 5 minutes, then filtered through a small plug of diatomaceous earth, washing with chloroform. The filtrate concentrated under reduced pressure to give 4-bromo-2-ethylphenyllead triacetate.

1. stirringthe mixture is stirred at 40° C. for 4 hours
2. temperatureThe reaction mixture is cooled to 0° C.
3. stirringThe mixture is stirred for 5 minutes
4. filtrationfiltered through a small plug of diatomaceous earth
5. washwashing with chloroform
6. concentrationThe filtrate concentrated under reduced pressure