Formic Acid → N-(2-Chloro-6-(2-chloro-6-nitrophenylthio)phenyl) formamide

HRID 408116Notes

Reaction equation

HRID 408116 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([S:9][C:10]2[C:15]([N+:16]([O-:18])=[O:17])=[CH:14][CH:13]=[CH:12][C:11]=2[Cl:19])[C:3]=1[NH2:4].[CH:20](O)=[O:21]>>[Cl:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([S:9][C:10]2[C:15]([N+:16]([O-:18])=[O:17])=[CH:14][CH:13]=[CH:12][C:11]=2[Cl:19])[C:3]=1[NH:4][CH:20]=[O:21]

Participants

3

Reactant 2

HCID 284Formic AcidHCID 682271432-Chloro-6-(2-chloro-6-nitrophenylthio)aniline

Product 1

HCID 86670894N-(2-Chloro-6-(2-chloro-6-nitrophenylthio)phenyl) formamide

Procedure

A solution of 2-chloro-6-(2-chloro-6-nitrophenylthio)aniline (689 mg, 2.18 mmol) in formic acid (5 mL) was heated at reflux for 16 hours. The mixture was allowed to cool to room temperature and the solvent was evaporated. The residue was used without purification.

Workup

  1. temperatureat reflux for 16 hours
  2. customthe solvent was evaporated
  3. customThe residue was used without purification

Sources & evidence

ORD record
ord-109483b018414b45bc19ae2b0726448b
Source dataset
uspto-grants-2014_06
Patent number
US08759336B2

Reaction notes

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