Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 408571Generated: October 29, 2026

Imidazo[1,2-a]pyridine-7-methanol → Imidazo[1,2-A]pyridine-7-carbaldehyde

https://huagongshe.com/reaction/408571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazo[1,2-a]pyridine-7-methanolHCID 11051824—
CatalystManganese dioxideHCID 14801—
SolventChloroformHCID 6212—
ProductImidazo[1,2-A]pyridine-7-carbaldehydeHCID 11029972—

Reaction Conditions

Temperature60 °C

Reaction Steps

To a solution of imidazo[1,2-a]pyridin-7-yl-methanol (1 eq.) in chloroform was added MnO2 (10 eq.). The dark suspension was heated at 60° C. for 30 min, filtered through a pad of celite and the solvent removed under reduced pressure to afford imidazo[1,2-a]pyridine-7-carbaldehyde which was used as such without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759334B2
Source datasetuspto-grants-2014_06
ORD IDord-87bbdba7e51c4a438546d48ff8f8ffc9
Source noteuspto-grants-2014_06