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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 408575Generated: October 29, 2026

Benzo[d]thiazol-5-ylmethanol → 1,3-Benzothiazole-5-carbaldehyde

https://huagongshe.com/reaction/408575

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo[d]thiazol-5-ylmethanolHCID 22281733—
CatalystManganese dioxideHCID 14801—
SolventDichloromethaneHCID 6344—
Product1,3-Benzothiazole-5-carbaldehydeHCID 21873718—

Reaction Conditions

Temperature20 °C

Reaction Steps

To a solution of benzothiazol-5-yl-methanol (1 eq.) in DCM was added MnO2 (10 eq.). The dark suspension was stirred at 20° C. for 15 h, filtered through a pad of celite and the solvent removed under reduced pressure to afford benzothiazole-5-carbaldehyde which was used as such without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759334B2
Source datasetuspto-grants-2014_06
ORD IDord-369831751b674dc4b9a51dbd8cf70f4a
Source noteuspto-grants-2014_06