HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 408610Generated: October 30, 2026
Methanol → Methyl azetidine-2-carboxylate hydrochloride
https://huagongshe.com/reaction/408610
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Azetidinecarboxylic Acid | HCID 17288 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Methyl azetidine-2-carboxylate hydrochloride | HCID 22476057 | — |
Reaction Steps
To a solution of azetidine-2-carboxylic acid (1 eq.) in MeOH at 0° C. was added dropwise thionyl chloride (2.5 eq.). The reaction was stirred at 20° C. for 15 h. The crude was concentrated under reduced pressure and used as such without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08759334B2 |
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| Source dataset | uspto-grants-2014_06 |
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| ORD ID | ord-7e083845b2e44d96834f03e73cf5b337 |
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| Source note | uspto-grants-2014_06 |
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