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HRID40866

反应详情

EQUATION

反应方程式

HRID 40866 的结构方程式

REACTANTS

反应物

2
结构：O=C[O-].[NH4+]
HCID2723923

Formic acid, ammonium salt

CH5NO2

结构：Cc1ccc(S(=O)(=O)n2cc(-c3nc(NC(C)C)ncc3C#N)c3cc(NC(=O)OCc4ccccc4)cnc32)cc1
HCID68668357

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(S(=O)(=O)n2cc(-c3nc(NC(C)C)ncc3C#N)c3cc(N)cnc32)cc1
HCID68668268

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Benzyl 3-(5-cyano-2-(isopropylamino)pyrimidin-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-ylcarbamate (0.199 g, 0.342 mmol) in EtOH (15 mL) was charged with ammonium formate (0.129 g, 2.055 mmol, 6.0 Eq) and 10% Pd/C (0.040 g, 0.2 Eq) and heated at reflux for 3 hours.

WORKUP

后处理

  1. temperatureheated
  2. temperatureat reflux for 3 hours