Trifluoroacetic acid → HCID 68724556, compound

HRID 408669Notes

Reaction equation

HRID 408669 reaction equation
C(OC(=O)[NH:7][CH:8]1[CH2:12][CH2:11][N:10]([C:13]2[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([O:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[CH:21]=3)[N:16]=[C:15]([CH3:30])[CH:14]=2)[CH2:9]1)(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[CH3:30][C:15]1[CH:14]=[C:13]([N:10]2[CH2:11][CH2:12][CH:8]([NH2:7])[CH2:9]2)[C:22]2[C:17](=[CH:18][CH:19]=[C:20]([O:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH:21]=2)[N:16]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 68776429HCID 68776429, compound

Product 1

HCID 68724556HCID 68724556, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The product from step (i) above was treated with trifluoroacetic acid in dichloromethane (1:1) to give, after evaporation, the title compound as an orange oil, which was used without further purification.

Workup

  1. customto give
  2. customafter evaporation
  3. customthe title compound as an orange oil, which was used without further purification

Sources & evidence

ORD record
ord-ecaa8839bc4a4b3e909a6acdeb4d32f9
Source dataset
uspto-grants-2014_06
Patent number
US08759348B2

Reaction notes

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