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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 408807Generated: October 25, 2026

Benzaldehyde → 6-Chloropurine

https://huagongshe.com/reaction/408807

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant6-Chloro-2-methylpyrimidine-4,5-diamineHCID 594145—
Product6-ChloropurineHCID 5359277—

Reaction Steps

In Step 1, 6-chloro-2-methyl-4,5-pyrimidinediamine is reacted with a benzaldehyde (3) to provide a 6-chloropurine (6), essentially as described in Scheme 1, Step 2, above. In Step 2, a 6-chloropurine (6) is reacted with a piperazine (5) to provide a piperazinyl purine (7) essentially as described in Scheme 1, Step 3, above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759360B2
Source datasetuspto-grants-2014_06
ORD IDord-df9457114dd6437c8f84e6afc3c24f31
Source noteuspto-grants-2014_06