反应详情

Tert-butyl 4-((5-(methoxycarbonyl)furan-2-yl)methyl)piperazine-1-carboxylate (4.99 g, 15.39 mmol) and sodium hydroxide (0.616 g, 15.39 mmol) were combined and stirred at reflux for 3 hours. The reaction was concentrated under reduced pressure to give the title compound (4.59 g). MS (ESI) m/z 311.4 [M+H]+

1. temperatureat reflux for 3 hours
2. concentrationThe reaction was concentrated under reduced pressure