HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-Ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-Ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide | HCID 86686109 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-Ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide hydrochloride | HCID 86686110 | — |
Reaction Steps
N-Ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide hydrochloride is obtained by adding 4N HCl in dioxane to N-ethyl-2-(4-piperidin-4-yl-phenyl)-propionamide (VI.1). The mixture is stirred for 1 h and the solvent is removed in vacuo. The residue is taken up in diethyl ether, stirred for 20 min and the solvent is evaporated to yield the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759528B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-d20590d955b746c6adfe4977379dff94 |
| Source note | uspto-grants-2014_06 |