Trifluoroacetic acid → Trifluoroacetic acid

Participants

Reaction Steps

A 50 mL round bottom flask was charged with a magnetic stirbar, Compound 12 (1.5 g, 6.11 mmol) and dichloromethane (25 mL). Trifluoroacetic acid (2.1 g, 18.3 mmol) was added and the reaction mixture was allowed to stir at room temperature for 4 hours. Solvent and volatiles were removed in vacuo overnight to yield Compound 13 as its TFA salt.

Provenance & Evidence