HuagongsheHuagongshe Chemistry Print Report · For research reference only
Resorcinol → Methyl 4-(2-(2,4-dihydroxyphenyl)-2-oxoethyl)-3-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | 2-(4-(Methoxycarbonyl)-2-methylphenyl)acetic acid | HCID 57555224 | — |
| Product | Methyl 4-(2-(2,4-dihydroxyphenyl)-2-oxoethyl)-3-methylbenzoate | HCID 67367578 | 69.6% |
Reaction Steps
2-(4-(methoxycarbonyl)-2-methylphenyl)acetic acid (295 mg) was treated with resorcinol (190 mg) in BF3Et2O at 90° C. over night. After aqueous work-up with ethyl acetate and column purification, the desired product (296 mg) was isolated as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759548B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-851cdde3192547e5acf1aebf59b0e674 |
| Source note | uspto-grants-2014_06 |