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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 410109Generated: October 26, 2026

Diisopropylcarbodiimide → HCID 178481223, compound

https://huagongshe.com/reaction/410109

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylcarbodiimideHCID 12734—
Reactant(2,4-Dichloro-3-isothiocyanato-benzyl)-carbamic acid tert-butyl esterHCID 56840196—
ReactantHCID 178482270HCID 178482270—
ProductHCID 178481223HCID 178481223—

Reaction Steps

The title compound is prepared from N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(2,2-difluoro-ethoxy)-4-methylamino-5-amino-benzoic acid amide and (2,4-dichloro-3-isothiocyanato-benzyl)-carbamic acid tert-butyl ester with DIC in analogy to examples 7b/7c.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759537B2
Source datasetuspto-grants-2014_06
ORD IDord-1d01e2bf72f145c0bfda437023c2ba4f
Source noteuspto-grants-2014_06