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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 410110Generated: October 30, 2026

Diisopropylcarbodiimide → HCID 178425577, compound

https://huagongshe.com/reaction/410110

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylcarbodiimideHCID 12734—
ReactantN-(2,4-Dimethyl-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamideHCID 56840195—
ReactantHCID 178482270HCID 178482270—
ProductHCID 178425577HCID 178425577—

Reaction Steps

The title compound is prepared from N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(2,2-difluoro-ethoxy)-4-methylamino-5-amino-benzoic acid amide and N-(2,4-dimethyl-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide with DIC in analogy to examples 7b/7c.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759537B2
Source datasetuspto-grants-2014_06
ORD IDord-f9498e1f36804d9eae59246354e0570d
Source noteuspto-grants-2014_06