HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 4-(Methylamino)-3-nitrobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-Fluoro-3-nitrobenzoic acid | HCID 67987 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-(Methylamino)-3-nitrobenzoic acid | HCID 283475 | — |
Reaction Steps
4-Methylamino-3-nitro-benzoic acid (825 mg) was prepared by following General Procedure A starting from 4-fluoro-3-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 8.1 mL) in THF. The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-705eeba1d51b4124a7575f0951cb9830 |
| Source note | uspto-grants-2014_06 |