HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N-methyl-3-(methylamino)-4-nitrobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-(Methylamino)-4-nitrobenzoic acid | HCID 22184623 | — |
| Solvent | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Product | N-methyl-3-(methylamino)-4-nitrobenzamide | HCID 60144426 | — |
Reaction Steps
N-Methyl-3-methylamino-4-nitro-benzamide (407 mg) was prepared by following General Procedure N starting from 3-methylamino-4-nitro-benzoic acid (500 mg), DPPA (550 uL), DIEA (445 uL), and methylamine (2 M in THF, 2.55 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-7d2304e356624088a78609476118870f |
| Source note | uspto-grants-2014_06 |