HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 2-Fluoro-4-(methylamino)-5-nitrobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2,4-Difluoro-5-nitrobenzoic acid | HCID 2782822 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Fluoro-4-(methylamino)-5-nitrobenzoic acid | HCID 59529834 | — |
Reaction Steps
2-Fluoro-4-methylamino-5-nitro-benzoic acid (750 mg) was prepared by following General Procedure A starting from 2,4-difluoro-5-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 2.46 mL) in THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-23bfe7fce064480ca62974a04a9828e1 |
| Source note | uspto-grants-2014_06 |