HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 6-Methylamino-5-nitro-nicotinic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl 6-chloro-5-nitronicotinate | HCID 3784053 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-Methylamino-5-nitro-nicotinic acid ethyl ester | HCID 67333371 | — |
Reaction Steps
6-Methylamino-5-nitro-nicotinic acid ethyl ester (911 mg) was prepared by following General Procedure A starting from 6-chloro-5-nitro-nicotinic acid ethyl ester (1.0 g) and methylamine (2 M in THF, 3.25 mL) in DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-5f49cee6d57241138c910b2c2ab6a4d2 |
| Source note | uspto-grants-2014_06 |