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HRID410795

反应详情

EQUATION

反应方程式

HRID 410795 的结构方程式

REACTANTS

反应物

2
结构：CN
HCID6329

Methylamine

CH5N

结构：CCOC(=O)c1cnc(Cl)c([N+](=O)[O-])c1
HCID3784053

Ethyl 6-chloro-5-nitronicotinate

C8H7ClN2O4

PRODUCTS

生成物

1
结构：CCOC(=O)c1cnc(NC)c([N+](=O)[O-])c1
HCID67333371

6-Methylamino-5-nitro-nicotinic acid ethyl ester

C9H11N3O4

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

6-Methylamino-5-nitro-nicotinic acid ethyl ester (911 mg) was prepared by following General Procedure A starting from 6-chloro-5-nitro-nicotinic acid ethyl ester (1.0 g) and methylamine (2 M in THF, 3.25 mL) in DMF.