HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methylamino-5-nitro-nicotinic acid ethyl ester → 5-Amino-6-methylamino-nicotinic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methylamino-5-nitro-nicotinic acid ethyl ester | HCID 67333371 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 5-Amino-6-methylamino-nicotinic acid ethyl ester | HCID 67334125 | 91.6% |
Reaction Steps
5-Amino-6-methylamino-nicotinic acid ethyl ester (723 mg) was prepared by following General Procedure B starting from 6-methylamino-5-nitro-nicotinic acid ethyl ester (911 mg) and Pd/C (10% by weight, 90 mg). The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-a4c38adfc2dc4e5ba655597fa0fdc514 |
| Source note | uspto-grants-2014_06 |