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HRID410844

反应详情

EQUATION

反应方程式

HRID 410844 的结构方程式

REACTANTS

反应物

3
结构：S=C(n1ccnc1)n1ccnc1
HCID80264

Thiocarbonyldiimidazole

C7H6N4S

结构：CS(=O)(=O)c1ccc2nc(N)sc2c1
HCID87152

6-(Methylsulfonyl)-2-benzothiazolamine

C8H8N2O2S2

结构：CNc1ccc(C(=O)OC)cc1N
HCID15586064

Methyl 3-amino-4-(methylamino)benzoate

C9H12N2O2

PRODUCTS

生成物

1
结构：COC(=O)c1ccc2c(c1)nc(Nc1nc3ccc(S(C)(=O)=O)cc3s1)n2C
HCID58397583

未命名化合物

收率 78.9%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCCl
溶剂HCID11

1,2-Dichloroethane

C2H4Cl2

PROCEDURE

实验过程

2-(6-Methanesulfonyl-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid methyl ester (1.64 g) was prepared by following General Procedure D starting from 3-amino-4-methylamino-benzoic acid methyl ester (0.9 g), 2-amino-6-methanesulfonyl-benzothiazole (1.14 g), 1,1′-thiocarbonyldiimidazole (1.07 g), and EDC (1.15 g). LC/MS: m/z 418.