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HRID410850

反应详情

EQUATION

反应方程式

HRID 410850 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)c1ccc2c(c1)nc(Nc1nc3cc(F)ccc3s1)n2C
HCID58397476

未命名化合物

PRODUCTS

生成物

1
结构：Cn1c(Nc2nc3cc(F)ccc3s2)nc2cc(C(=O)O)ccc21
HCID58397592

未命名化合物

收率 89.5%

PROCEDURE

实验过程

2-(5-Fluoro-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid (1.53 g) was prepared by following General Procedure E starting from 2-(5-fluoro-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid methyl ester (1.78 g), and LiOH (10.0 ml, 2.0 N solution in water). LC/MS: m/z 344.