Lithium Hydroxide → 2-(6-Methanesulfonyl-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Lithium Hydroxide	HCID 3939	—
Edukt	2-(6-Methanesulfonyl-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid methyl ester	HCID 58397583	—
Produkt	2-(6-Methanesulfonyl-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid	HCID 53356438	87,1%

Reaktionsschritte

2-(6-Methanesulfonyl-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid (1.75 g) was prepared by following General Procedure E starting from 2-(6-methanesulfonyl-benzothiazol-2-ylamino)-1-methyl-1H-benzimidazole-5-carboxylic acid methyl ester (2.08 g), and LiOH (10.0 ml, 2.0 N solution in water). LC/MS: m/z 404.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08759535B2
Quelldatensatz	uspto-grants-2014_06
ORD ID	ord-8b10c63877de44e4aa3bc0537498ecda
Quellennotiz	uspto-grants-2014_06