HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Isopropylamino-3-nitro-benzoic acid methyl ester → Methyl 3-Amino-4-(Isopropylamino)Benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Isopropylamino-3-nitro-benzoic acid methyl ester | HCID 2823414 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | Methyl 3-Amino-4-(Isopropylamino)Benzoate | HCID 2736795 | 89% |
Reaction Steps
3-Amino-4-isopropylamino-benzoic acid methyl ester (700.0 mg) was prepared by following General Procedure B starting from 4-isopropylamino-3-nitro-benzoic acid methyl ester (900.0 mg) and Pd/C (20% by weight, 180.0 mg) in MeOH:EtOAc (1:1, 10.0 mL). The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-89419a633a5b401fa745458e45fd0e58 |
| Source note | uspto-grants-2014_06 |