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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 410902Generated: October 30, 2026

2-Methoxyethylamine → Methyl 4-((2-methoxyethyl)amino)-3-nitrobenzoate

https://huagongshe.com/reaction/410902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethylamineHCID 8018—
ReactantMethyl 4-chloro-3-nitrobenzoateHCID 735797—
SolventDimethylformamideHCID 6228—
ProductMethyl 4-((2-methoxyethyl)amino)-3-nitrobenzoateHCID 6733521481.4%

Reaction Steps

4-(2-Methoxy-ethylamino)-3-nitro-benzoic acid methyl ester (960.0 mg) was prepared by following General Procedure A starting from methyl 4-chloro-3-nitrobenzoate (1.0 g) and 2-methoxy-ethylamine (413.0 mg) in DMF (10.0 mL). The crude product was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759535B2
Source datasetuspto-grants-2014_06
ORD IDord-2d6bd3c84a2c4c2eb409de875b20f45e
Source noteuspto-grants-2014_06