HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 4-(Methylamino)-3-nitrobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-Fluoro-2-methyl-3-nitrobenzonitrile | HCID 67333528 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(Methylamino)-3-nitrobenzonitrile | HCID 4600715 | — |
Reaction Steps
4-Methylamino-3-nitro-benzonitrile (1.69 mg) was prepared by following General Procedure A starting from methyl 4-fluoro-3-nitrobenzonitrile (1.66 g) and methylamine (2 M in THF, 10.0 mL) in DMF. The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-76818ce622944b4d8ce748b6f0782d42 |
| Source note | uspto-grants-2014_06 |