HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1-[4-(Methylamino)-3-nitrophenyl]ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-(4-Fluoro-3-nitrophenyl)propan-1-one | HCID 53429561 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-[4-(Methylamino)-3-nitrophenyl]ethan-1-one | HCID 13175626 | — |
Reaction Steps
1-(4-Methylamino-3-nitro-phenyl)-ethanone (153 mg) was prepared by following General Procedure A starting from methyl 1-(4-fluoro-3-nitro-phenyl)-ethanone (183 mg) and methylamine (2 M in THF, 1.0 ml) in DMF (5 mL). The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-a17ca1bab8414d6b9c8a975d903ef7a1 |
| Source note | uspto-grants-2014_06 |