HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → (4-Methanesulfonyl-2-nitro-phenyl)methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-Fluoro-4-methanesulfonyl-2-nitrobenzene | HCID 313137 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (4-Methanesulfonyl-2-nitro-phenyl)methyl-amine | HCID 44518858 | — |
Reaction Steps
(4-Methanesulfonyl-2-nitro-phenyl)methyl-amine (182 mg) was prepared by following General Procedure A starting from 1-fluoro-4-methanesulfonyl-2-nitro-benzene (219 mg) and methylamine (2 M in THF, 1.0 ml) in DMF (5 mL). The crude product was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-a2c85c829b5f41c3b433ff9774433725 |
| Source note | uspto-grants-2014_06 |