4-(Methanesulfonyl)-N-methyl-2-nitroaniline → 4-(Methanesulfonyl)-N~1~-methylbenzene-1,2-diamine

HRID 410956Notes

Reaction equation

HRID 410956 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([NH:11][CH3:12])=[C:7]([N+:13]([O-])=O)[CH:6]=1)(=[O:4])=[O:3]>[Pd]>[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([NH2:13])[C:8]([NH:11][CH3:12])=[CH:9][CH:10]=1)(=[O:3])=[O:4]

Participants

3

Reactant 1

HCID 1216904-(Methanesulfonyl)-N-methyl-2-nitroaniline

Product 1

HCID 205512544-(Methanesulfonyl)-N~1~-methylbenzene-1,2-diamineYield 76%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

4-Methanesulfonyl-N1-methyl-benzene-1,2-diamine (76 mg) was prepared by following General Procedure B starting from (4-methanesulfonyl-2-nitro-phenyl)-methyl-amine (115 mg) and Pd/C (10% by weight, 10 mg). The crude product was used in the next step without further purification.

Workup

  1. customThe crude product was used in the next step without further purification

Sources & evidence

ORD record
ord-672daa86a6b946c487977ede04cde21c
Source dataset
uspto-grants-2014_06
Patent number
US08759535B2

Reaction notes

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