HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → Ethyl 3-(methylamino)-4-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl 3-Fluoro-4-nitrobenzoate | HCID 45036938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 3-(methylamino)-4-nitrobenzoate | HCID 67333336 | — |
Reaction Steps
3-Methylamino-4-nitro-benzoic acid ethyl ester (2.8 g) was prepared by following General Procedure A starting from 3-fluoro-4-nitro-benzoic acid ethyl ester (3 g) and 2 M methylamine in THF (15 mL) in DMF (15 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-295c70fa03584261aea92be3011633e9 |
| Source note | uspto-grants-2014_06 |