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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411035Generated: October 30, 2026

HCID 86656957, compound → HCID 86656921, compound

https://huagongshe.com/reaction/411035

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86656957HCID 86656957—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 86656921HCID 86656921258.8%

Reaction Steps

2-(6-Chloro-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid (R)-pyrrolidin-3-ylamide dihydrochloride (45 mg) was prepared by following General Procedure L starting from (R)-3-{[2-(6-chloro-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carbonyl]-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester (55 mg) in 4M HCl in dioxane (1 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759535B2
Source datasetuspto-grants-2014_06
ORD IDord-11e5089567c44ab6b0eb42ec7db84799
Source noteuspto-grants-2014_06