Thionyl Chloride → 4-(Methylamino)-3-nitrobenzoyl chloride

HRID 411049Notes

Reaction equation

HRID 411049 reaction equation
[CH3:1][NH:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13].S(Cl)([Cl:17])=O>>[CH3:1][NH:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:17])=[O:8])=[CH:5][C:4]=1[N+:12]([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 2834754-(Methylamino)-3-nitrobenzoic acid

Product 1

HCID 179464494-(Methylamino)-3-nitrobenzoyl chloride

Conditions

Temperature
80 °C

Procedure

4-Methylamino-3-nitro-benzoyl chloride (4.3 g) was prepared starting from 4-methylamino-3-nitro-benzoic acid (4 g) in thionyl chloride (20 mL). The reaction was heated to 80° C. for 8 h. The solvent was evaporated to isolate pure compound without any further purification.

Workup

  1. customThe solvent was evaporated
  2. customto isolate pure compound
  3. customwithout any further purification

Sources & evidence

ORD record
ord-cf67af8299fd443997516bc33d342552
Source dataset
uspto-grants-2014_06
Patent number
US08759535B2

Reaction notes

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